Risk Factor as a Central Concept in CARRE

Cardiorenal disease and comorbidities is a complex domain. Related conditions do not have a single cause, but evidence suggests that there are multiple causal chains. In order to capture this in CARRE, current evidence will be presented as a complex network of risk factors, that is, pairs of conditions one related to another via a…

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An Overview of the CARRE Medical Domain

CARRE will address the specific medical domain of cardiorenal disease and comorbidities as this is a very common, life threatening and costly condition and because it also presents a number of challenges and opportunities for the demonstration of CARRE outcomes. Cardiorenal syndrome (CRS) is the condition characterised by simultaneous kidney and heart failure while the…

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